Open Letter to MacKenzie Scott and Dan Jewett

December 23, 2023

Dear Mr. Jewett and Mrs. Scott,

Your remarkable generosity is changing the entire area of philanthropy. In the meantime, the field of healthcare and life science is still awaiting dramatic changes. The life science field is the focal point where technology meets humanity. Progress of life sciences can give our kids the opportunity to live actively for 150-200 years. On the other hand, it carries the risks of misuse. I invented a technology, which  enables the former and mitigates the risks of the latter.

I am Dr. Alexander Asanov, the inventor of i-Diagnostics (http://i-diagnostics.net), a platform technology for the precision medicine of the future. Being inspired by Dr. Albert Bruce Sabin, who made his invention of polio vaccine available for all, I am willing to make i-Diagnostics available to everyone. I received my training from four Nobel Prize winners, elite super-talented teachers, and dozens of genius scientists; they enabled me with the unique set of skills and knowledge that I am not taking for granted. I pledge to return them back to society – make my inventions in the area of precision medicine available for all. Together with i-Diagnostics we supply to our R&D customers the entire range of tools for application development. I am giving back to society my knowledge, skills, and labor. But they reach only a limited number of groups. Your donations will help us to make i-Diagnostics an Open Source Platform available to the broadest base of scientific and medical communities; in several years i-Diagnostics will be available to everyone. 

In 2007, I invented the TIRF microarray technology and now I see how our customers use it to diagnose diseases in their research labs, discover new drugs and repurpose old ones, such as Ivermectin, for prophylactics and treatment for COVID-19, study the mechanisms at the level of single molecules, and develop cures for diseases. I am delighted to share my products and technologies. But at the present time only a few research groups can afford sophisticated TIRF products. With your donations our efforts could be amplified tremendously, thousands of research groups worldwide will develop their diagnostic applications, discover new biological markers, and find new cures. 

Unlike conventional tests that detect only one class of biomarkers, i-Diagnostics detects all 4 major classes simultaneously: DNA, RNA, proteins, and metabolites, and builds 4D images of the response, providing superior accuracy for personalized medicine. The US government granted me $4.3M for Phase 1 and my team of scientists and engineers has developed not only i-Diagnostics, but also a broad-range of analytical-grade TIRF instruments (TIRF-Labs.com ). We are ready to move to Phase 2 and request your donations to make i-Diagnostics an Open Source Platform in order to make it affordable for thousands of research groups and create an infrastructure based on the intelligence of the global network of scientists and medical doctors to mitigate the risks of emergence and outbreaks of diseases. Technologically, it is already feasible. Please visit our website www.i-diagnostics.net for details and contact us via email i-diagnostics@tirf-labs.com. Donate to the i-Diagnostics project to change the future of medicine to be a step ahead of any disease. Thank you. 

Sincerely, 

Alexander Asanov, Ph.D., CEO, TIRF Labs