Copyright © 2012-2019 TIRF Labs, Inc. All photographic images, schemes and text located at this web site are copyrighted by TIRF Labs, Inc. To use them, please contact us with your request: Include a description of the purpose and location for placement.  • Terms and ConditionsPrivacy Policy   

iDiagnostics is the future of precision medicine. With your help we will make iDiagnostics available for all. Additionally, iDiagnostics will help to minimize the risk of humanity self-eradication. iDiagnostics employs TIRF microarray technology; to learn more about TIRF visit

 iDiagnostics for All

nonprofit project, which goal is to develop advanced molecular diagnostics for home use

to reduce the damages caused by naturally occurring diseases  and

to minimize the risks of humanity self-eradication by biological technologies

In collaboration

with  TIRF Labs


Use the uTIRF as a turnkey station, or take prism-, lightguide-, or objective-TIRF units to use as add-on accessories for your microscope

uTIRF - the ultimate TIRF microscopy turnkey station

uTIRF Brochure.pdf

Application notes and published papers

uTIRF turnkey station consists of prism-, lightguide-, and objective-based TIRF,  infinity objective 20X, 40X, 60X, or 100X,  low light CMOS camera, and a multicolor fiber-coupled illuminator. uTIRF is available in several configurations with open perfusion and closed flow chambers, optional electrochemical and dielectrophoretic control. Prism-, lightguide-, and objective-TIRF units can be taken from uTIRF to be used as add-on accessories for fluorescence microscopes. Inquire about other options.

Main Pros / Cons of  TIRF geometries  (for details click here)






The cleanest TIRF effect - stray light<0.01%. Can be used with dry, water-, and oil-immersion objectives.

No open perfusion for prism-down geometry.



Clean TIRF effect - stray light <0.1%.

Can be used with dry, water-, and oil-immersion objectives.

TIRF area needs to be aligned with the objective.



TIRF area stays with the objective.

Evanescent wave contaminated by 10-15% of stray light.